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Cultivos celulares
Stem Cell Research Announcement
Publicación sobre la investigación de cultivos celulares
Researchers Identify Adult Cells That Mimic Embryonic Stem Cells
Investigadores identifican células de adulto que imitan a las células embrionarias.
LOUISVILLE, Ky. – In a discovery that has the potential to change the face of stem cell research, a University of Louisville scientist has identified cells in the adult body that seem to behave like embryonic stem cells.
En un descubimiento que tiene el potencial para cambiar la cara a la investigación de cultivos celulares, científicos de la Universidad de Lousville han identificado células en el cuerpo de adultos que parecen comportarse como las células de embriones.
The cells, drawn from adult bone marrow, look like embryonic stem cells and appear to mimic their ability to multiply and develop into other kinds of cells, said Mariusz Ratajczak, director of the stem cell biology program at U of L’s James Graham Brown Cancer Center, who led the research project.
Estas células que se obtienen de la medulla espinal de adultos, se asemejan a las células embrionarias e imitan la habilidad de multiplicarse y desarrollarse en otro tipo de células. Así dijo Mariuz Ratajczak, director del programa de biología en cultivos celulares en el Centro De Cancer de la UL de James Graham Brown, quién también dirige el proyecto de investigación.
The finding, presented at the 47th Annual Meeting of the American Society of Hematology (ASH) in Atlanta, was announced December 12 at the society’s news conference.
Estos resultados, presentados en el 47vo encuentro anual de la Sociedad Americana de hematología (ASH) en Atlanta, fueron pubicados el diciembre 12 en la conferencia para los medios noticiosos.
A study by Ratajczak’s team published last year in the journal “Leukemia” was the first to identify a type of stem cell in adult bone marrow that acts differently than other marrow stem cells. The newly-identified cells, called “very small embryonic-like” (VSEL) stem cells, have the same structure and protein markers as embryonic stem cells.
Un estudio hecho por el grupo de Ratajczak publicado el año pasado en la revista “Leucemia” fué el primero en identificar un tipo de células para cultivo en la médulla espinal de adultos, que actúa en forma diferente que las otras células de la médulla. Las nuevas células identificadas, llamadas “muy pequeña célula tipo embrionaria (VSEL)”, tienen la misma estructura y proteinas marcadoras que las células embrionarias.
Ratajczak and several other researchers from U of L made a presentation at the ASH meeting showing that VSEL stem cells mobilize into the bloodstream to help repair damaged tissue following a stroke.
Ratajczak y algunos otros investigadores de la UL hicieron una presentación en la reunion del ASH mostrando que las VSEL se movilizan en el torrente sanguíneo para ayudar a reparar los tejidos después de una apoplejía.
Ratajczak’s team also has grown VSEL cells in a lab and has stimulated them to change into nerve, heart and pancreas cells. If other scientists can duplicate the process on a larger scale, it could reduce the need for embryonic stem cells in research and eliminate rejection problems associated with using stem cells from an outside donor.
El equipo de Ratajczak también ha crecido células VSEL en el laboratorio y las ha estimulado para cambiarlas en células de nervios, corazón y pancreas. Si otros científicos pueden duplicar el proceso en mayor escala, reducirá la necesidad de usar células embrionarias para la investigación y eliminará los problemas de rechazo asociados con el uso de cultivos celulares de un donador externo.
“We are very excited about the tremendous implications of this discovery,” Ratajczak said. “Our preliminary success in growing and differentiating these cells is very encouraging.”
”Estamos muy entusiasmados en relación a las implicaciones de este descubrimiento”, dijo Ratajczak. “ Nuestro éxito preliminar en diferenciar y crecer estas células nos anima mucho.
Researchers worldwide have said that various types of stem cells hold great promise for understanding and treating a wide variety of diseases. The use of embryonic stem cells, which can evolve into any type of cell in the body, has been surrounded by controversy.
Investigadores del mundo han dicho que varios tipos de células guardan grandes promesas para entender y tratar una gran variedad de enfermedades. El uso de células embrionarias, que pueden cambiar en cualquier tipo de células en el cuerpo, ha estado rodeado por controversias.